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Astrazeneca (AZN) Q1 Earnings: Taking a Look at Key Metrics Versus Estimates

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Astrazeneca (AZN - Free Report) reported $15.29 billion in revenue for the quarter ended March 2026, representing a year-over-year increase of 12.5%. EPS of $2.58 for the same period compares to $2.48 a year ago.

The reported revenue represents a surprise of +2.18% over the Zacks Consensus Estimate of $14.96 billion. With the consensus EPS estimate being $2.57, the EPS surprise was +0.39%.

While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine their next move, some key metrics always offer a more accurate picture of a company's financial health.

Since these metrics play a crucial role in driving the top- and bottom-line numbers, comparing them with the year-ago numbers and what analysts estimated about them helps investors better project a stock's price performance.

Here is how Astrazeneca performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
  • BioPharmaceuticals- R&I- Symbicort- U.S.: $290 million versus $274.82 million estimated by two analysts on average. Compared to the year-ago quarter, this number represents a +3.9% change.
  • Oncology- Others- Europe: $4 million versus the two-analyst average estimate of $4.76 million. The reported number represents a year-over-year change of +33.3%.
  • BioPharmaceuticals- CVRM- Crestor- U.S.: $8 million compared to the $9.18 million average estimate based on two analysts. The reported number represents a change of -33.3% year over year.
  • Oncology- Zoladex- U.S.: $5 million versus the two-analyst average estimate of $5.33 million.
  • Alliance Revenue- Total: $825 million versus $877.66 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a +29.1% change.
  • Collaboration Revenue- Total: $77 million versus $50.08 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a +4.1% change.
  • BioPharmaceuticals- R&I- Symbicort- World: $747 million versus the two-analyst average estimate of $734.02 million. The reported number represents a year-over-year change of +3.3%.
  • BioPharmaceuticals- R&I- Pulmicort- World: $149 million versus the two-analyst average estimate of $138.76 million. The reported number represents a year-over-year change of -5.7%.
  • BioPharmaceuticals- CVRM- Crestor- World: $354 million versus $330.74 million estimated by two analysts on average. Compared to the year-ago quarter, this number represents a +12% change.
  • BioPharmaceuticals- CVRM- Seloken/Toprol-XL- World: $180 million versus $166.86 million estimated by two analysts on average. Compared to the year-ago quarter, this number represents a +11.8% change.
  • Oncology- Zoladex- World: $304 million versus the two-analyst average estimate of $300.55 million.
  • Oncology- Tagrisso- World: $1.83 billion versus $1.86 billion estimated by two analysts on average. Compared to the year-ago quarter, this number represents a +9.2% change.

View all Key Company Metrics for Astrazeneca here>>>

Shares of Astrazeneca have returned -5.3% over the past month versus the Zacks S&P 500 composite's +12.2% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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